Karl E Anderson Selected Research

Hydro-Lyases (Dehydratases)

5/2024	From chemistry to genomics: A concise history of the porphyrias.
1/2022	Case Report: Lack of Response to Givosiran in a Case of ALAD Porphyria.
12/2020	5-Aminolevulinate dehydratase porphyria: Update on hepatic 5-aminolevulinic acid synthase induction and long-term response to hemin.
1/2006	Dual gene defects involving delta-aminolaevulinate dehydratase and coproporphyrinogen oxidase in a porphyria patient.

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Karl E Anderson Research Topics

Disease

17	Porphyrias (Porphyria) 05/2024 - 01/2006
15	Acute Intermittent Porphyria (Porphyria, Acute) 05/2024 - 09/2004
12	Erythropoietic Protoporphyria 04/2023 - 06/2002
8	Porphyria Cutanea Tarda 01/2023 - 02/2002
5	Phototoxic Dermatitis (Phototoxicity) 02/2024 - 08/2010
4	Hepatic Porphyrias (Hepatic Porphyria) 01/2022 - 10/2017
4	Infections 01/2022 - 02/2002
4	Neoplasms (Cancer) 01/2021 - 07/2005
3	Liver Diseases (Liver Disease) 01/2023 - 04/2013
3	Breast Neoplasms (Breast Cancer) 12/2022 - 07/2007
3	Hereditary Coproporphyria (Coproporphyrinogen Oxidase Deficiency) 01/2022 - 01/2006
3	Pain (Aches) 11/2020 - 03/2005
3	Hemochromatosis (Bronze Diabetes) 11/2019 - 02/2002
3	HIV Infections (HIV Infection) 03/2011 - 02/2002
2	Chronic Hepatitis C 01/2023 - 03/2010
2	Fibrosis (Cirrhosis) 01/2022 - 08/2010
2	Disease Progression 01/2022 - 12/2020
2	Paresis (Hemiparesis) 01/2022 - 03/2005
2	Body Weight (Weight, Body) 11/2020 - 01/2019
2	Lead Poisoning (Poisoning, Lead) 12/2015 - 09/2004
2	Hepatitis C 03/2011 - 02/2002
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2009 - 02/2009
1	Blister (Bulla) 01/2023
1	Anemia 12/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2022
1	COVID-19 01/2022
1	Rare Diseases (Rare Disease) 01/2022
1	Neurologic Manifestations (Neurological Manifestations) 01/2022
1	Lithiasis 01/2022
1	Abdominal Pain (Pain, Abdominal) 01/2022
1	Carcinogenesis 01/2021
1	Metabolic Diseases (Metabolic Disease) 01/2021
1	Myeloproliferative Disorders (Myeloproliferative Disorder) 12/2020
1	Hyperbilirubinemia 12/2020
1	Polycythemia Vera 12/2020
1	Injection Site Reaction 11/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2020
1	Hypoxia (Hypoxemia) 11/2019
1	Hepatoerythropoietic Porphyria 11/2019
1	Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency) 11/2019
1	Cardiovascular Diseases (Cardiovascular Disease) 12/2018
1	Myocardial Infarction 12/2018
1	Stroke (Strokes) 12/2018
1	Pulmonary Embolism 12/2018
1	Renal Insufficiency (Renal Failure) 06/2017
1	Liver Failure 02/2016

Drug/Important Bio-Agent (IBA)

15	Heme (Haem)IBA 05/2024 - 03/2005
10	protoporphyrin IXIBA 02/2024 - 06/2002
8	EnzymesIBA 01/2022 - 10/2017
7	PorphyrinsIBA 05/2024 - 08/2010
7	Hemin (Panhematin)FDA Link 01/2022 - 03/2005
5	PorphobilinogenIBA 05/2024 - 01/2006
5	Ferrochelatase (Heme Synthetase)IBA 01/2021 - 06/2002
5	Uroporphyrinogen Decarboxylase (Uroporphyrinogen III Decarboxylase)IBA 11/2019 - 02/2002
4	Aminolevulinic Acid (Levulan)FDA Link 05/2024 - 09/2018
4	Hydro-Lyases (Dehydratases)IBA 05/2024 - 01/2006
4	IronIBA 12/2022 - 12/2012
4	Acute Hepatic PorphyriaIBA 01/2022 - 01/2020
4	AcidsIBA 01/2022 - 09/2004
4	givosiranIBA 01/2022 - 01/2019
3	Biomarkers (Surrogate Marker)IBA 12/2022 - 07/2007
3	IsoflavonesIBA 12/2022 - 07/2005
3	Adenosine Diphosphate (ADP)IBA 01/2022 - 04/2006
3	Coproporphyrinogen Oxidase (Coproporphyrinogen III Oxidases)IBA 01/2022 - 01/2006
3	Estrogens (Estrogen)FDA Link 03/2011 - 02/2002
2	MetalsIBA 04/2023 - 12/2015
2	CreatinineIBA 01/2023 - 11/2020
2	CalciumIBA 12/2022 - 12/2018
2	Ethanol (Ethyl Alcohol)IBA 03/2011 - 03/2010
2	Glucose (Dextrose)FDA LinkGeneric 06/2009 - 03/2005
2	SteroidsIBA 06/2009 - 02/2009
1	Dioctyl Sulfosuccinic Acid (DOSS)IBA 05/2024
1	sofosbuvir drug combination ledipasvirIBA 01/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023
1	Sunscreening Agents (Sunscreens)IBA 01/2023
1	AntioxidantsIBA 01/2023
1	Hormones (Hormone)IBA 12/2022
1	PorphyrinogensIBA 01/2022
1	Small Interfering RNA (siRNA)IBA 01/2022
1	fibulin 2IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Tamoxifen FDA LinkGeneric 01/2021
1	IntegrinsIBA 01/2021
1	Conditioned Culture MediaIBA 01/2021
1	Transaminases (Aminotransferases)IBA 11/2020
1	Hydroxymethylbilane Synthase (Porphobilinogen Deaminase)IBA 11/2019
1	Protoporphyrinogen Oxidase (Protox)IBA 11/2019
1	GasesIBA 11/2019
1	Isoniazid (Ftivazide)FDA LinkGeneric 11/2019
1	Messenger RNA (mRNA)IBA 01/2019
1	zinc protoporphyrinIBA 12/2015

Therapy/Procedure

5	Therapeutics 01/2023 - 01/2019
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2023 - 06/2002
2	Liver Transplantation 01/2021 - 06/2015
1	Phototherapy (Light Therapy) 01/2023
1	Intravenous Administration 11/2020
1	RNAi Therapeutics 11/2020
1	Injections 01/2019
1	Subcutaneous Injections 01/2019
1	Renal Dialysis (Hemodialysis) 06/2017